GHRP-6
GHRP-6 is the earlier of the two GHRP compounds, a hexapeptide widely used as a reference secretagogue in growth-hormone research.
Also known as: Growth hormone releasing peptide-6
Research context
- One of the earliest synthetic GH secretagogues.
- Also noted for appetite-stimulating effects in research.
- Available in 5mg and 10mg.
Full breakdown below: what it is • the category • common questions
What GHRP-6 is
GHRP-6 (growth hormone-releasing peptide-6) is a synthetic ghrelin-receptor agonist with a broader secretagogue profile than GHRP-2: alongside growth hormone release, published work documents effects on insulin signalling and cortisol pathway signalling. That broader activity is exactly the distinction — where GHRP-2 was designed for receptor selectivity, GHRP-6 is the compound used in research when the question involves those additional pathways.
Where it sits in the secretagogue category
| Compound | Receptor / class | Activity character | Clinical documentation |
|---|---|---|---|
| GHRP-6 | Ghrelin-receptor agonist | Broader: GH release plus insulin and cortisol-pathway signalling effects | Preclinical + early-phase |
| GHRP-2 | Ghrelin-receptor agonist | Selective for the ghrelin receptor; minimal prolactin/ACTH effect | Preclinical + early-phase |
| Ipamorelin | Ghrelin-receptor agonist | Selective; the most handled compound on this side of the shelf | Clinical studies; not approved as a product |
| CJC-1295 (no DAC) | GHRH analogue | Acts on a different receptor (GHRH receptor) — complementary, not interchangeable | Preclinical + early-phase |
The practical takeaway: if the research question involves the insulin or cortisol signalling arms as well as GH release, GHRP-6 is the compound that covers them. For single-receptor selectivity, that is GHRP-2 or ipamorelin.
How it is supplied and handled
GHRP-6 ships as a lyophilised (freeze-dried) powder in a sealed vial — the standard stable form for research peptides. It is available here in 5mg and 10mg vials. Once reconstituted with bacteriostatic water it should be kept refrigerated and handled cold-chain; the reconstitution guide covers the volumes, arithmetic and storage handling for this class of compound. Every batch is supplied with a certificate of analysis (see the lab and COA policy); batch-specific COAs can be requested via the contact page before ordering.
Ordering, payment and delivery
Pricing is per single vial — no minimum order. Card checkout runs on Stripe; bank transfer is available at 10% off and confirms on clearance. UK dispatch is cold-chain, and delivery sets out the timelines and what to expect on arrival.
Common questions
What is the difference between GHRP-6 and GHRP-2?
Both are ghrelin-receptor agonists, but GHRP-6 has broader secretagogue activity — published work documents effects on insulin and cortisol-pathway signalling in addition to GH release — while GHRP-2 is more selective for the ghrelin receptor alone.
Why would a protocol choose GHRP-6 over ipamorelin?
When the research question involves the insulin or cortisol signalling arms as well as GH release, GHRP-6 covers those pathways; ipamorelin is the selective single-receptor choice. Both are preclinical-to-early-phase compounds on this side of the shelf.
Does GHRP-6 affect anything besides growth hormone?
Yes — that is its defining character. Published work documents broader secretagogue activity on insulin and cortisol-pathway signalling alongside GH release, which is the main research reason to use it instead of a selective ghrelin-receptor agonist.
What strengths do you stock and how do I pay?
5mg at £5.61 (bank £5.05) and 10mg at £9.35 (bank £8.41). No minimum order; card checkout runs on Stripe, bank orders confirm on clearance.
Can GHRP-6 be combined with a GHRH analogue?
In research protocols, yes — it acts on the ghrelin receptor, so it is complementary to GHRH-receptor compounds like CJC-1295 and tesamorelin rather than redundant.
Is GHRP-6 a medicine?
As sold here it is a research chemical. It is not a licensed medicine in the UK, it is not for human or veterinary use, and nothing on this page is medical advice or a dosing recommendation.