TB-500
TB-500 is a synthetic fragment of thymosin beta-4. It is most often researched alongside BPC-157 rather than on its own.
Also known as: Thymosin Beta-4 fragment
Research context
- Fragment of the naturally occurring protein thymosin beta-4.
- Commonly combined with BPC-157 in research protocols.
- Available in 5mg and 10mg.
What TB-500 is
TB-500 is a synthetic fragment of thymosin beta-4 (Tβ4), a small protein found in most cell types. The fragment corresponds to the active region of the parent molecule, which is why it is used in research as a compact, well-defined stand-in for the full-length protein rather than as a molecule in its own right.
Thymosin beta-4 is best known in the literature for its actin-binding behaviour: it sequesters monomeric actin, and it is studied in the context of cell migration, tissue remodelling and repair signalling. TB-500 isolates the region responsible for that behaviour, which is what makes it practical to handle as a lyophilised research peptide.
Why it is almost always researched alongside BPC-157
TB-500 is rarely a standalone question. The two compounds are studied together because they probe overlapping but distinct parts of the repair process, so a combined design can ask a question neither compound answers alone — which is why our pre-mixed BPC-157 + TB-500 vial exists, alongside the standalone BPC-157.
If the research question is about a single defined pathway, start with the specific compound. If it is about how two repair-relevant mechanisms interact, the combination is the more natural design — and the muscle recovery guide sets out how the compounds in this class are positioned relative to each other.
TB-500 vs other compounds in this category
| Compound | Class | Where it differs |
|---|---|---|
| BPC-157 | Stable gastric pentadecapeptide | A different molecule entirely, studied through the angiogenic / nitric-oxide pathway rather than actin binding — complementary, not interchangeable. |
| BPC-157 + TB-500 | Combination vial | The same two compounds supplied together for research designs that need both in one vial. |
| GHK-Cu | Copper-binding tripeptide | A short copper peptide studied in a separate remodelling context — different scale, different mechanism. |
The practical takeaway: TB-500 is the actin-binding arm of the repair category. Where a study needs the angiogenic side of the picture as well, BPC-157 is the compound it is normally paired with.
How it is supplied and handled
TB-500 ships as a lyophilised (freeze-dried) powder in a sealed vial — the standard stable form for research peptides. It is available here in 5mg and 10mg vials. Once reconstituted with bacteriostatic water it should be kept refrigerated and handled cold-chain; the general reconstitution guide covers the volumes, the arithmetic and the storage handling that apply to this class of compound.
Every batch is supplied with a certificate of analysis. Our lab and COA policy explains what is tested and what the documentation covers — if you need a batch-specific COA before ordering, ask via the contact page and we will send it.
Ordering, payment and delivery
Pricing is per single vial — no minimum order and no bundle you have to take to get a sensible rate. Card checkout runs on Stripe; bank transfer is available at 10% off and confirms on clearance. UK dispatch is cold-chain, and delivery sets out the timelines and what to expect on arrival.
Common questions
What is TB-500?
TB-500 is a synthetic fragment of thymosin beta-4, corresponding to the active region of the parent protein. It is studied for the actin-binding behaviour associated with Tβ4, in cell-migration and tissue-repair research.
Is TB-500 a research chemical or a medicine?
As sold here, it is a research chemical. It is not a licensed medicine in the UK, it is not for human or veterinary use, and nothing on this page is medical advice or a dosing recommendation.
What is the difference between TB-500 and BPC-157?
They are different molecules studied through different mechanisms. TB-500 is the actin-binding thymosin beta-4 fragment; BPC-157 is a gastric pentadecapeptide studied through the angiogenic / nitric-oxide pathway. Because they probe different parts of the repair process, they are frequently researched together.
Do you sell TB-500 and BPC-157 together?
Yes — a combined BPC-157 + TB-500 vial is available if you want both compounds in one product, alongside the standalone versions.
What strengths do you stock?
5mg and 10mg vials. The 5mg is £14.45 and the 10mg is £23.80 per vial, with a 10% discount on bank transfer.
Does it come with a COA, and how is it shipped?
Yes — a certificate of analysis accompanies every batch and is available on request before you order. It ships as lyophilised powder with cold-chain UK dispatch; see the delivery page for timelines.